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A/B Testing Cold Emails: Best Practices

  • Silvio Bonomi
  • Mar 17
  • 6 min read

Updated: Apr 1


Key Takeaways:

  • What to Test: Subject lines, email openings, value statements, CTAs, and design elements.
  • Metrics to Track: Open rate (15-25%), response rate (5-15%), click-through rate (2-5%), and meeting conversions (20-30%).
  • Testing Tools: Tools like HubSpot, Mailchimp, Lemlist, and GMass simplify A/B testing.
  • How to Test: Change one element at a time, use a large enough sample size, and track results for 7-10 days.

A/B testing helps you refine your email strategy, engage your audience better, and drive more meetings. Ready to dive in? Let’s break it down.


Test Setup Steps


Choosing Test Variables

Focus on testing to clearly understand its impact. Some key elements to consider include:

  • Subject lines
  • Opening paragraphs
  • Call-to-action placement and wording
  • Sender name format (e.g., first name vs. full name)
  • Email signature style

Keep everything else consistent while changing just one element. Also, make sure your sample size is large enough to ensure reliable outcomes.


Determining Sample Size

A larger test group will yield more accurate results. If your email list is small, consider extending your testing period to gather enough data.

Once your sample is ready, select the right tools to execute your tests.


Tools and Software for Testing

There are plenty of tools with built-in A/B testing features to streamline the process. Here are some options:

Enterprise Tools

  • HubSpot Sales Hub: Offers advanced A/B analytics.
  • Mailchimp: Includes automated winner selection.
  • Outreach.io: Ideal for testing sales sequences.

Small Business Tools

  • Lemlist: Features an easy-to-use interface and engagement tracking.
  • GMass: Provides Gmail-based testing capabilities.
  • Woodpecker: Specializes in automated follow-up testing.

Look for features like automated send time optimization, real-time tracking, and tools that calculate statistical significance. These will help you efficiently test subject lines, email content, and calls-to-action.



Subject Line Testing Guide

Subject line testing is key to improving cold email open rates. Let’s look at some proven techniques to increase engagement.


Personal vs. Interest-Based Lines

When crafting subject lines, compare personalized options with interest-driven ones to see what connects better with your audience.

Personalization Elements to Try:

  • Including the recipient's first name or full name
  • Placing the company name at the start or end
  • Referencing their industry
  • Tailoring the message to their role

Interest-Based Elements to Try:

  • Framing it as a problem-solution
  • Highlighting a clear value proposition
  • Asking a question
  • Focusing on specific benefits

For example, test a personalized subject like against an interest-based one such as Keep the length and format similar, changing only the main focus.

Once you’ve tested these, dive into the technical details of formatting and style.


Format and Style Tests

The way your subject line is formatted can also influence open rates. Experiment with these elements:

Optimizing Length

  • Keep mobile users in mind by aiming for 30-50 characters
  • Test short (3-4 words) versus medium (6-8 words) subject lines
  • Compare truncated lines with fully visible ones

Formatting Features

  • Try different capitalization styles, like Title Case or Sentence case
  • Experiment with punctuation, such as question marks or ellipses
  • Use numbers (e.g., "10%" vs. "ten percent") to see what performs better
  • Play with emoji placement - at the beginning or end of the line

Testing Tips:

  • Send each variant to at least 200 recipients
  • Stick to the same send times for all tests
  • Schedule emails during standard business hours (9 AM to 5 PM in the recipient's time zone)
  • Wait 48-72 hours to gather reliable results

Email Content Testing Methods

Refining your email body can significantly improve engagement. Here are some effective ways to test and optimize different parts of your email content.


First Line Tests

The first line of your email sets the tone and grabs attention. Experiment with these strategies:

  • Personalized ContextReference a recent company update, mention a mutual connection, or address specific challenges related to the recipient’s role.
  • Direct ValueStart with a compelling statistic, ask a thought-provoking question, or highlight an immediate benefit.

Personalizing the opening line with relevant milestones or industry issues often outperforms generic greetings.


Value Statement Position

Where you place your value proposition can shape how your message is received. Try these approaches:

  • Top-loaded ValueBegin with your most important benefit in the opening paragraph, followed by supporting details. This works well for busy professionals.
  • Problem-Solution StructureIntroduce a challenge, outline the issue, and then present your solution. Spread this over two or three concise paragraphs for clarity.
  • Benefit SandwichStart and end with strong value statements, placing credentials and supporting details in between.

Once you’ve fine-tuned your value statement, focus on improving your call-to-action.


Call-to-Action Tests

Your call-to-action (CTA) is key to driving conversions. Test these variables:

  • Placement: Try positioning the CTA at the end or within the email body.
  • Format: Compare buttons to text links to see which gets more clicks.
  • Language: Test straightforward prompts against conversational phrasing.
  • Time Commitment: Experiment with specific time requests versus open-ended invitations.

These tests can help you pinpoint the most effective CTA for your audience.


Key Testing Guidelines

  • Run tests for at least a week.
  • Use a sample size of at least 100 emails per variant.
  • Keep email length consistent across versions.
  • Test one element at a time to ensure clear results.

Incorporating these methods into your email campaigns can lead to measurable improvements in performance.


Results Analysis and Implementation


Reading Test Results

When analyzing test results, focus on metrics that align closely with your campaign goals. Key areas to evaluate include:

  • Open rates: Look at percentage differences between your test variants.
  • Click-through rates (CTR): Assess how well your content encourages engagement.
  • Response rates: Measure the number of replies you receive from recipients.
  • Meeting conversion: Track the number of successful meeting bookings.

For reliable data, run tests for at least 7–10 business days, sending no fewer than 200 emails. Ensure emails are evenly distributed and sent at consistent times. Use these findings to fine-tune your messaging.


Applying Results to Other Campaigns

Once you’ve identified what works, apply those winning strategies across your other campaigns. Consistency is key to maximizing success.

Build a library of proven elements to streamline future efforts:

  • Subject Lines: Keep a record of styles and approaches that perform well.
  • Opening Lines: Note introductions that grab attention effectively.
  • Value Propositions: Highlight phrasing that resonates with your audience.
  • CTAs: Document formats that drive the highest conversions.

Segment your data based on factors like industry, company size, decision-maker level, and region to tailor your approach even further.


Regular Testing Schedule

To stay ahead, maintain a consistent testing routine. A structured schedule ensures you’re always optimizing:

1. Monthly Tests

Focus on one specific element each month, such as subject lines or CTAs, to test meaningful variables.

2. Quarterly Reviews

Every quarter, review your results to spot trends and refine your strategies.

3. Annual Optimization

Conduct a yearly audit of your test outcomes. Use this time to update best practices, identify new testing opportunities, adjust priorities, and set fresh benchmarks.

Tracking your testing schedule helps you build a solid foundation of historical data. Keep in mind that email performance can shift over time due to changing audience preferences and market conditions. Regular testing ensures your approach stays effective and relevant.


Key Testing Guidelines

A/B testing works best when approached methodically, with clear goals in mind. Stick to these core practices:

  • Test only one variable at a time to isolate what works.
  • Ensure your sample sizes are large enough to produce reliable results.
  • Track actionable metrics like open rates, click-through rates, response rates, and conversions.
  • Keep a record of what works - save successful subject lines, openings, and value propositions for future use.
  • Stick to a regular testing schedule to maintain consistency.

Remember, the ultimate goal is closing deals, not testing for testing's sake. If testing feels overwhelming or time-consuming, expert help can make the process smoother.


Professional Help Options

When your team lacks the bandwidth for detailed testing, professional lead generation services can make a difference. For example, Artemis Leads offers tailored support, including:

  • Crafting Ideal Customer Profiles (ICPs) to target the right audience.
  • Finding and qualifying prospects that match your ICPs.
  • Running multichannel campaigns via email and LinkedIn.
  • Scheduling sales meetings with decision-makers who are ready to talk.

Their multilingual approach ensures effective communication across various markets. By combining expertise in email testing with a structured lead qualification process, services like Artemis Leads let your team focus on closing deals - not the nitty-gritty of email campaigns.

If you're short on time or resources for A/B testing or lead generation, partnering with specialists can help you run more effective campaigns and secure better leads.


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